Breeze offers direct flights from Jacksonville to 11 cities. The most frequent destinations are: Norfolk, Hartford, Providence, San Diego and Columbus.

Allegiant offers direct flights from Jacksonville to 9 cities. The most frequent destinations are: Des Moines, Cincinnati, Knoxville, Belleville and Akron.

American offers direct flights from Jacksonville to 7 cities. The most frequent destinations are: Charlotte, Dallas, Miami, Washington and Philadelphia.

Southwest offers direct flights from Jacksonville to 7 cities. The most frequent destinations are: Baltimore, Nashville, St. Louis, Denver and Chicago.

Delta offers direct flights from Jacksonville to 6 cities. The most frequent destinations are: Atlanta, New York, Boston, Detroit and Minneapolis.

United offers direct flights from Jacksonville to 5 cities. The most frequent destinations are: Newark, Houston, Washington, Chicago and Denver.